REACH Revision 2024/2025: Mixture Allocation Factor (MAF)

27 June 2023

The proposed REACH revision introduces a new provision, the Mixture Allocation Factor (MAF). The concept of the MAF has been introduced in the risk management of chemical substances to consider adverse (eco)toxicological effects from different sources of exposure to the same substance (multi-exposures) and for several different substances (cocktail effect). The proposal intends to address the issue that most individual registrants do not know much about other uses of the same substances registered by competitors, and that they do not know how users of their substances, the general population and the environment are exposed to other substances.