Assessment of the Genotoxicity and Carcinogenicity of 2-Chloroethanol Published

Date: 27 July  2022

For the current risk assessment of 2-chloroethanol (2-CE) residues in food, Regulation (EC) 396/2005 requires 2-CE to be assessed in the same way as ethylene oxide (EO), which is classified as a genotoxic carcinogen. A group of scientists, including SCC toxicologists Thomas Roth and Henrike Peuschel, have recently assessed the existing genotoxicity and carcinogenicity data and data on structural analogues of 2-CE. They concluded that 2-CE is not a genotoxic carcinogen which makes read-across to EO for risk assessment purposes highly questionable. You can read the online article here.